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A molecular blueprint for the pore-forming structure of voltage-gated calcium channels.

A protein that imitates the sequence of a highly conserved segment predicted to line the pore of dihydropyridine-sensitive L-type calcium channels was designed and synthesized. Single-channel conductance properties were studied in planar lipid bilayers. The synthetic protein emulates the ionic condu...

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Bibliografiska uppgifter
Huvudupphovsmän: Grove, A, Tomich, J M, Montal, M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1991
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC52096/
https://ncbi.nlm.nih.gov/pubmed/1713679
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