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Concentration of Donepezil in the Cerebrospinal Fluid of AD Patients: Evaluation of Dosage Sufficiency in Standard Treatment Strategy

Although some studies have described the pharmacokinetics and pharmacodynamics of donepezil in the peripheral compartment, studies focused on drug transport across the blood–brain barrier are still very rare. To our knowledge, the fluctuation in the cerebrospinal fluid concentration of donepezil aft...

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Vydáno v:Neurotox Res
Hlavní autoři: Valis, Martin, Masopust, Jiri, Vysata, Oldrich, Hort, Jakub, Dolezal, Rafael, Tomek, Jiri, Misik, Jan, Kuca, Kamil, Karasova, Jana Zdarova
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209410/
https://ncbi.nlm.nih.gov/pubmed/27718143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-016-9672-y
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