Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging

In multiple sclerosis (MS), iron accumulates inside activated microglia/macrophages at edges of some chronic demyelinated lesions, forming rims. In susceptibility-based magnetic resonance imaging at 7 T, iron-laden microglia/macrophages induce a rim of decreased signal at lesion edges and have been...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol
Autori principali: Dal-Bianco, Assunta, Grabner, Günther, Kronnerwetter, Claudia, Weber, Michael, Höftberger, Romana, Berger, Thomas, Auff, Eduard, Leutmezer, Fritz, Trattnig, Siegfried, Lassmann, Hans, Bagnato, Francesca, Hametner, Simon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2016
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209400/
https://ncbi.nlm.nih.gov/pubmed/27796537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1636-z
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