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Endoplasmic Reticulum Protein Quality Control Failure in Myelin Disorders
Reaching the correct three-dimensional structure is crucial for the proper function of a protein. The endoplasmic reticulum (ER) is the organelle where secreted and transmembrane proteins are synthesized and folded. To guarantee high fidelity of protein synthesis and maturation in the ER, cells have...
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Publicado no: | Front Mol Neurosci |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5209374/ https://ncbi.nlm.nih.gov/pubmed/28101003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00162 |
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