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Plasma Membrane Targeting of Endogenous NKCC2 in COS7 Cells Bypasses Functional Golgi Cisternae and Complex N-Glycosylation
Na(+)K(+)2Cl(−) co-transporters (NKCCs) effect the electroneutral movement of Na(+)-K(+) and 2Cl(−) ions across the plasma membrane of vertebrate cells. There are two known NKCC isoforms, NKCC1 (Slc12a2) and NKCC2 (Slc12a1). NKCC1 is a ubiquitously expressed transporter involved in cell volume regul...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5209364/ https://ncbi.nlm.nih.gov/pubmed/28101499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00150 |
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