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Tissue injury caused by deposition of immune complexes is L-arginine dependent.

Nitric oxide (NO.), a free radical that is generated from L-arginine by stimulated endothelial cells, neutrophils, activated macrophages, and other cell types, reacts with superoxide anion (O2.-) to form peroxynitrite, which itself may be tissue toxic or can then react further to form the highly rea...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Mulligan, M S, Hevel, J M, Marletta, M A, Ward, P A
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52078/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1648737/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.14.6338
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