Tissue injury caused by deposition of immune complexes is L-arginine dependent.
Nitric oxide (NO.), a free radical that is generated from L-arginine by stimulated endothelial cells, neutrophils, activated macrophages, and other cell types, reacts with superoxide anion (O2.-) to form peroxynitrite, which itself may be tissue toxic or can then react further to form the highly rea...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1991
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52078/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1648737/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.14.6338 |
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