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HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization

Sensitive and specific genotyping of human papillomaviruses (HPVs) is important for population-based surveillance of carcinogenic HPV types and for monitoring vaccine effectiveness. Here we compare HPV genotyping by Next Generation Sequencing (NGS) to an established DNA hybridization method. In DNA...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Meisal, Roger, Rounge, Trine Ballestad, Christiansen, Irene Kraus, Eieland, Alexander Kirkeby, Worren, Merete Molton, Molden, Tor Faksvaag, Kommedal, Øyvind, Hovig, Eivind, Leegaard, Truls Michael, Ambur, Ole Herman
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207713/
https://ncbi.nlm.nih.gov/pubmed/28045981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169074
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