A Phase II single-arm trial of palonosetron for the prevention of acute and delayed chemotherapy-induced nausea and vomiting in malignant glioma patients receiving multidose irinotecan in combination with bevacizumab

PURPOSE: Given that the prognosis of recurrent malignant glioma (MG) remains poor, improving quality of life (QoL) through symptom management is important. Meta-analyses establishing antiemetic guidelines have demonstrated the superiority of palonosetron (PAL) over older 5-hydroxytryptamine 3-recept...

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Detalhes bibliográficos
Publicado no:Ther Clin Risk Manag
Main Authors: Affronti, Mary Lou, Woodring, Sarah, Peters, Katherine B, Herndon, James E, McSherry, Frances, Healy, Patrick N, Desjardins, Annick, Vredenburgh, James J, Friedman, Henry S
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207433/
https://ncbi.nlm.nih.gov/pubmed/28096679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S122480
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