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Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model

Hypoxia is an important physiological stress signal that drives angiogenesis, the formation of new blood vessels. Besides an increase in the production of pro-angiogenic signals such as vascular endothelial growth factor (VEGF), hypoxia also stimulates the production of anti-angiogenic signals. Thro...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Zhao, Chen, Isenberg, Jeffrey S., Popel, Aleksander S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207393/
https://ncbi.nlm.nih.gov/pubmed/28045898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005272
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