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Plastic germline reprogramming of heritable small RNAs enables maintenance or erasure of epigenetic memories

In Caenorhabditis elegans small RNAs can regulate genes across generations. The mysterious tendency of heritable RNA interference (RNAi) responses to terminate after 3–5 generations has been referred to as “the bottleneck to RNAi inheritance.” We have recently shown that the re-setting of epigenetic...

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Vydáno v:RNA Biol
Hlavní autoři: Houri-Ze'evi, Leah, Rechavi, Oded
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207387/
https://ncbi.nlm.nih.gov/pubmed/27592591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1229732
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