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In vitro evolution of chemically-modified nucleic acid aptamers: Pros and cons, and comprehensive selection strategies
Nucleic acid aptamers are single-stranded DNA or RNA oligonucleotide sequences that bind to a specific target molecule with high affinity and specificity through their ability to adopt 3-dimensional structure in solution. Aptamers have huge potential as targeted therapeutics, diagnostics, delivery a...
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| Publicado no: | RNA Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5207382/ https://ncbi.nlm.nih.gov/pubmed/27715478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1236173 |
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