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Human intron-encoded AluACA RNAs and telomerase RNA share a common element promoting RNA accumulation

Mammalian cells express hundreds of intron-encoded box H/ACA RNAs which fold into a common hairpin-hinge-hairpin-tail structure, interact with 4 evolutionarily conserved proteins, dyskerin, Nop10, Nhp2 and Gar1, and function mainly in RNA pseudouridylation. The human telomerase H/ACA RNA (hTR) direc...

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Détails bibliographiques
Publié dans:RNA Biol
Auteurs principaux: Ketele, Amandine, Kiss, Tamás, Jády, Beáta E.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207380/
https://ncbi.nlm.nih.gov/pubmed/27726486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1239689
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