Structure of the Shroom-Rho Kinase Complex Reveals a Binding Interface with Monomeric Shroom That Regulates Cell Morphology and Stimulates Kinase Activity

Shroom-mediated remodeling of the actomyosin cytoskeleton is a critical driver of cellular shape and tissue morphology that underlies the development of many tissues including the neural tube, eye, intestines, and vasculature. Shroom uses a conserved SD2 domain to direct the subcellular localization...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Zalewski, Jenna K., Mo, Joshua H., Heber, Simone, Heroux, Annie, Gardner, Richard G., Hildebrand, Jeffrey D., VanDemark, Andrew P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207239/
https://ncbi.nlm.nih.gov/pubmed/27758857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738559
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak