The N-terminal Ankyrin Repeat Domain Is Not Required for Electrophile and Heat Activation of the Purified Mosquito TRPA1 Receptor

Temperature sensors are crucial for animals to optimize living conditions. The temperature response of the ion channel transient receptor potential A1 (TRPA1) is intriguing; some orthologs have been reported to be activated by cold and others by heat, but the molecular mechanisms responsible for its...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Survery, Sabeen, Moparthi, Lavanya, Kjellbom, Per, Högestätt, Edward D., Zygmunt, Peter M., Johanson, Urban
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2016
Ämnen:
Membrane Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207195/
https://ncbi.nlm.nih.gov/pubmed/27875296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.743443
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