The N-terminal Ankyrin Repeat Domain Is Not Required for Electrophile and Heat Activation of the Purified Mosquito TRPA1 Receptor

Temperature sensors are crucial for animals to optimize living conditions. The temperature response of the ion channel transient receptor potential A1 (TRPA1) is intriguing; some orthologs have been reported to be activated by cold and others by heat, but the molecular mechanisms responsible for its...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Survery, Sabeen, Moparthi, Lavanya, Kjellbom, Per, Högestätt, Edward D., Zygmunt, Peter M., Johanson, Urban
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Membrane Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207195/
https://ncbi.nlm.nih.gov/pubmed/27875296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.743443
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