Substrate Trapping in Crystals of the Thiolase OleA Identifies Three Channels That Enable Long Chain Olefin Biosynthesis

Phylogenetically diverse microbes that produce long chain, olefinic hydrocarbons have received much attention as possible sources of renewable energy biocatalysts. One enzyme that is critical for this process is OleA, a thiolase superfamily enzyme that condenses two fatty acyl-CoA substrates to prod...

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Spremljeno u:
Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Goblirsch, Brandon R., Jensen, Matthew R., Mohamed, Fatuma A., Wackett, Lawrence P., Wilmot, Carrie M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Enzymology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207179/
https://ncbi.nlm.nih.gov/pubmed/27815501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.760892
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