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A Conserved Tripeptide Sequence at the C Terminus of the Poxvirus DNA Processivity Factor D4 Is Essential for Protein Integrity and Function

Vaccinia virus (VACV) is a poxvirus, and the VACV D4 protein serves both as a uracil-DNA glycosylase and as an essential component required for processive DNA synthesis. The VACV A20 protein has no known catalytic function itself but associates with D4 to form the D4-A20 heterodimer that functions a...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nuth, Manunya, Guan, Hancheng, Ricciardi, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207139/
https://ncbi.nlm.nih.gov/pubmed/27836975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.761908
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