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Induced pluripotent stem cell generation from a man carrying a complex chromosomal rearrangement as a genetic model for infertility studies

Despite progress in human reproductive biology, the cause of male infertility often remains unknown, due to the lack of appropriate and convenient in vitro models of meiosis. Induced pluripotent stem cells (iPSCs) derived from the cells of infertile patients could provide a gold standard model for g...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Mouka, Aurélie, Izard, Vincent, Tachdjian, Gérard, Brisset, Sophie, Yates, Frank, Mayeur, Anne, Drévillon, Loïc, Jarray, Rafika, Leboulch, Philippe, Maouche-Chrétien, Leila, Tosca, Lucie
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206619/
https://ncbi.nlm.nih.gov/pubmed/28045072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39760
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