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Assembly of long error-prone reads using de Bruijn graphs

The recent breakthroughs in assembling long error-prone reads were based on the overlap-layout-consensus (OLC) approach and did not utilize the strengths of the alternative de Bruijn graph approach to genome assembly. Moreover, these studies often assume that applications of the de Bruijn graph appr...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Lin, Yu, Yuan, Jeffrey, Kolmogorov, Mikhail, Shen, Max W., Chaisson, Mark, Pevzner, Pavel A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206522/
https://ncbi.nlm.nih.gov/pubmed/27956617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604560113
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