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Clarifying intact 3D tissues on a microfluidic chip for high-throughput structural analysis

On-chip imaging of intact three-dimensional tissues within microfluidic devices is fundamentally hindered by intratissue optical scattering, which impedes their use as tissue models for high-throughput screening assays. Here, we engineered a microfluidic system that preserves and converts tissues in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Yih Yang, Silva, Pamuditha N., Syed, Abdullah Muhammad, Sindhwani, Shrey, Rocheleau, Jonathan V., Chan, Warren C. W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206515/
https://ncbi.nlm.nih.gov/pubmed/27956625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609569114
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