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Age and testosterone mediate influenza pathogenesis in male mice

Influenza severity increases with age, with hospitalization and mortality rates during seasonal influenza epidemics being higher in older men than age-matched women. As it is known that with age, circulating testosterone levels decline in males, we hypothesized that reduced testosterone contributes...

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Detalles Bibliográficos
Publicado en:Am J Physiol Lung Cell Mol Physiol
Main Authors: vom Steeg, Landon G., Vermillion, Meghan S., Hall, Olivia J., Alam, Ornob, McFarland, Ross, Chen, Haolin, Zirkin, Barry, Klein, Sabra L.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206399/
https://ncbi.nlm.nih.gov/pubmed/27815260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00352.2016
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