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Ebselen does not improve oxidative stress and vascular function in patients with diabetes: a randomized, crossover trial

Oxidative stress is a key driver of vascular dysfunction in diabetes mellitus. Ebselen is a glutathione peroxidase mimetic. A single-site, randomized, double-masked, placebo-controlled, crossover trial was carried out in 26 patients with type 1 or type 2 diabetes to evaluate effects of high-dose ebs...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Beckman, Joshua A., Goldfine, Allison B., Leopold, Jane A., Creager, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206349/
https://ncbi.nlm.nih.gov/pubmed/27765750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00504.2016
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