Physiological and hypoxic oxygen concentration differentially regulates human c-Kit(+) cardiac stem cell proliferation and migration

Cardiac stem cells (CSCs) are being evaluated for their efficacy in the treatment of heart failure. However, numerous factors impair the exogenously delivered cells' regenerative capabilities. Hypoxia is one stress that contributes to inadequate tissue repair. Here, we tested the hypothesis tha...

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Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: Bellio, Michael A., Rodrigues, Claudia O., Landin, Ana Marie, Hatzistergos, Konstantinos E., Kuznetsov, Jeffim, Florea, Victoria, Valasaki, Krystalenia, Khan, Aisha, Hare, Joshua M., Schulman, Ivonne Hernandez
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
Integrative Cardiovascular Physiology and Pathophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206337/
https://ncbi.nlm.nih.gov/pubmed/27694215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00449.2016
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