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Ion channel mechanisms of rat tail artery contraction-relaxation by menthol involving, respectively, TRPM8 activation and L-type Ca(2+) channel inhibition

Transient receptor potential melastatin 8 (TRPM8) is the principal cold and menthol receptor channel. Characterized primarily for its cold-sensing role in sensory neurons, it is expressed and functional in several nonneuronal tissues, including vasculature. We previously demonstrated that menthol ca...

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Publicado en:Am J Physiol Heart Circ Physiol
Autores principales: Melanaphy, Donal, Johnson, Christopher D., Kustov, Maxim V., Watson, Conall A., Borysova, Lyudmyla, Burdyga, Theodor V., Zholos, Alexander V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206336/
https://ncbi.nlm.nih.gov/pubmed/27765744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00222.2015
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