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Isoprenoid modification of rab proteins terminating in CC or CXC motifs.

Mevalonate starvation of hamster fibroblasts resulted in a shift of rab1b from the membrane to the cytosolic fraction, suggesting that rab1b depends upon an isoprenoid modification for its membrane localization. rab1b and rab3a proteins expressed in insect cells incorporated a product of [3H]mevalon...

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Bibliographic Details
Main Authors: Khosravi-Far, R, Lutz, R J, Cox, A D, Conroy, L, Bourne, J R, Sinensky, M, Balch, W E, Buss, J E, Der, C J
Format: Artigo
Language:Inglês
Published: 1991
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC52063/
https://ncbi.nlm.nih.gov/pubmed/1648736
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