Sirtuin-2 inhibition affects hippocampal functions and sodium butyrate ameliorates the reduction in novel object memory, cell proliferation, and neuroblast differentiation

We investigated the effects of the sirtuin-2 (SIRT2) inhibitor AK-7 on novel object memory, cell proliferation, and neuroblast differentiation in the dentate gyrus. In addition, we also observed the relationships with sodium butyrate, a histone deacetylase inhibitor, on the hippocampal functions. To...

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Publicado no:Lab Anim Res
Main Authors: Jung, Hyo Young, Yoo, Dae Young, Kim, Jong Whi, Kim, Dae Won, Choi, Jung Hoon, Chung, Jin Young, Won, Moo-Ho, Yoon, Yeo Sung, Hwang, In Koo
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Association for Laboratory Animal Science 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206229/
https://ncbi.nlm.nih.gov/pubmed/28053616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5625/lar.2016.32.4.224
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