Reduced β-Cell Secretory Capacity in Pancreatic-Insufficient, but Not Pancreatic-Sufficient, Cystic Fibrosis Despite Normal Glucose Tolerance

Patients with pancreatic-insufficient cystic fibrosis (PI-CF) are at increased risk for developing diabetes. We determined β-cell secretory capacity and insulin secretory rates from glucose-potentiated arginine and mixed-meal tolerance tests (MMTTs), respectively, in pancreatic-sufficient cystic fib...

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Bibliographic Details
Published in:Diabetes
Main Authors: Sheikh, Saba, Gudipaty, Lalitha, De Leon, Diva D., Hadjiliadis, Denis, Kubrak, Christina, Rosenfeld, Nora K., Nyirjesy, Sarah C., Peleckis, Amy J., Malik, Saloni, Stefanovski, Darko, Cuchel, Marina, Rubenstein, Ronald C., Kelly, Andrea, Rickels, Michael R.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2017
Subjects:
Pathophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204312/
https://ncbi.nlm.nih.gov/pubmed/27495225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0394
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