Short-term treatment with nitrate is not sufficient to induce in vivo antithrombotic effects in rats and mice

In humans, short-term supplementation with nitrate is hypotensive and inhibits platelet aggregation via an nitric oxide (NO)-dependent mechanism. In the present work, we analyzed whether short-term treatment with nitrate induces antithrombotic effects in rats and mice. Arterial thrombosis was evoked...

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Detalhes bibliográficos
Publicado no:Naunyn Schmiedebergs Arch Pharmacol
Main Authors: Kramkowski, K., Leszczynska, A., Przyborowski, K., Proniewski, B., Marcinczyk, N., Rykaczewska, U., Jarmoc, D., Chabielska, E., Chlopicki, S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203854/
https://ncbi.nlm.nih.gov/pubmed/27743016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-016-1308-5
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