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Interplay of Toll-Like Receptor 9, Myeloid Cells, and Deubiquitinase A20 in Periodontal Inflammation

Toll-like receptor 9 (TLR9)-deficient (TLR9(−/−)) mice are resistant to periodontitis, a disease characterized by a dysbiotic microbiota and deregulated immune response and resulting in tooth loss and various systemic conditions. However, the mechanisms and biological pathways by which TLR9 instigat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Crump, Katie E., Oakley, Jennifer C., Xia-Juan, Xia, Madu, Theandra C., Devaki, Swathi, Mooney, Erin C., Sahingur, Sinem E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203663/
https://ncbi.nlm.nih.gov/pubmed/27849177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00814-16
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