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Immunity Provided by an Outer Membrane Vesicle Cholera Vaccine Is Due to O-Antigen-Specific Antibodies Inhibiting Bacterial Motility

An outer membrane vesicle (OMV)-based cholera vaccine is highly efficacious in preventing intestinal colonization in the suckling mouse model. Immunity from OMVs comes from immunoglobulin (Ig), particularly IgG, in the milk of mucosally immunized dams. Anti-OMV IgG renders Vibrio cholerae organisms...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Wang, Zhu, Lazinski, David W., Camilli, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203661/
https://ncbi.nlm.nih.gov/pubmed/27795359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00626-16
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