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Immunity Provided by an Outer Membrane Vesicle Cholera Vaccine Is Due to O-Antigen-Specific Antibodies Inhibiting Bacterial Motility

An outer membrane vesicle (OMV)-based cholera vaccine is highly efficacious in preventing intestinal colonization in the suckling mouse model. Immunity from OMVs comes from immunoglobulin (Ig), particularly IgG, in the milk of mucosally immunized dams. Anti-OMV IgG renders Vibrio cholerae organisms...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Wang, Zhu, Lazinski, David W., Camilli, Andrew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203661/
https://ncbi.nlm.nih.gov/pubmed/27795359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00626-16
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