Retinoic acid is a negative regulator of AP-1-responsive genes.

We present evidence that retinoic acid can down-regulate transcriptional activation by the nuclear protooncogene c-jun. All three members of the retinoic acid receptor (RAR) subfamily (RAR alpha, RAR beta, and RAR gamma) can repress transcriptional induction of the human collagenase gene or a hetero...

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Bibliografiske detaljer
Main Authors: Schüle, R, Rangarajan, P, Yang, N, Kliewer, S, Ransone, L J, Bolado, J, Verma, I M, Evans, R M
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC52028/
https://ncbi.nlm.nih.gov/pubmed/1648728
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