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Cholesterol reducing agents inhibit assembly of type I parainfluenza viruses

Many enveloped RNA viruses utilize lipid rafts for the assembly of progeny virions, but the role of cholesterol, a major component of rafts, on paramyxovirus budding and virion formation is controversial. In this study, we analyzed the effects of FDA-approved cholesterol-reducing agents, gemfibrozil...

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Dades bibliogràfiques
Publicat a:Virology
Autors principals: Bajimaya, Shringkhala, Hayashi, Tsuyoshi, Frankl, Tünde, Bryk, Peter, Ward, Brian, Takimoto, Toru
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201439/
https://ncbi.nlm.nih.gov/pubmed/27915128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.11.011
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