Adequate immune response ensured by binary IL-2 and graded CD25 expression in a murine transfer model

The IL-2/IL-2Ralpha (CD25) axis is of central importance for the interplay of effector and regulatory T cells. Nevertheless, the question how different antigen loads are translated into appropriate IL-2 production to ensure adequate responses against pathogens remains largely unexplored. Here we fin...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fuhrmann, Franziska, Lischke, Timo, Gross, Fridolin, Scheel, Tobias, Bauer, Laura, Kalim, Khalid Wasim, Radbruch, Andreas, Herzel, Hanspeter, Hutloff, Andreas, Baumgrass, Ria
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Computational and Systems Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201416/
https://ncbi.nlm.nih.gov/pubmed/28035902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20616
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