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Subchronic Toxicities of HZ1006, a Hydroxamate-Based Histone Deacetylase Inhibitor, in Beagle Dogs and Sprague-Dawley Rats

Histone deacetylase inhibitors (HDACIs), such as vorinostat and panobinostat, have been shown to have active effects on many hematologic malignancies, including multiple myeloma and cutaneous T-cell lymphoma. Hydroxamate-based (Hb) HDACIs have very good toxicity profiles and are currently being test...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Int J Environ Res Public Health
मुख्य लेखकों: Zhang, Xiaofang, Zhang, Xiaodong, Yuan, Bojun, Ren, Lijun, Zhang, Tianbao, Lu, Guocai
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201331/
https://ncbi.nlm.nih.gov/pubmed/27916918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijerph13121190
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