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Induction of miR-96 by Dietary Saturated Fatty Acids Exacerbates Hepatic Insulin Resistance through the Suppression of INSR and IRS-1

Obesity is defined as the excessive accumulation of body fat that ultimately leads to chronic metabolic diseases. Diets rich in saturated fatty acids (SFA) exacerbate obesity and hepatic steatosis, which increase the risk of hepatic insulin resistance and type 2 diabetes (T2DM). Although microRNAs (...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yang, Won-Mo, Min, Kyung-Ho, Lee, Wan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201257/
https://ncbi.nlm.nih.gov/pubmed/28036389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169039
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