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Contribution of Polycomb group proteins to olfactory basal stem cell self-renewal in a novel c-KIT(+) culture model and in vivo

Olfactory epithelium (OE) has a lifelong capacity for neurogenesis due to the presence of basal stem cells. Despite the ability to generate short-term cultures, the successful in vitro expansion of purified stem cells from adult OE has not been reported. We sought to establish expansion-competent OE...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Goldstein, Bradley J., Goss, Garrett M., Choi, Rhea, Saur, Dieter, Seidler, Barbara, Hare, Joshua M., Chaudhari, Nirupa
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201051/
https://ncbi.nlm.nih.gov/pubmed/27789621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.142653
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