Cancer cells become less deformable and more invasive with activation of β-adrenergic signaling

Invasion by cancer cells is a crucial step in metastasis. An oversimplified view in the literature is that cancer cells become more deformable as they become more invasive. β-adrenergic receptor (βAR) signaling drives invasion and metastasis, but the effects on cell deformability are not known. Here...

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Veröffentlicht in:J Cell Sci
Hauptverfasser: Kim, Tae-Hyung, Gill, Navjot Kaur, Nyberg, Kendra D., Nguyen, Angelyn V., Hohlbauch, Sophia V., Geisse, Nicholas A., Nowell, Cameron J., Sloan, Erica K., Rowat, Amy C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201020/
https://ncbi.nlm.nih.gov/pubmed/27875276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.194803
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