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Role of innate and adaptive immunity in obesity-associated metabolic disease

Chronic inflammation in adipose tissue, possibly related to adipose cell hypertrophy, hypoxia, and/or intestinal leakage of bacteria and their metabolic products, likely plays a critical role in the development of obesity-associated insulin resistance (IR). Cells of both the innate and adaptive immu...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: McLaughlin, Tracey, Ackerman, Shelley E., Shen, Lei, Engleman, Edgar
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199693/
https://ncbi.nlm.nih.gov/pubmed/28045397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88876
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