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The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis

There are three dominant contributors to the pathogenesis of dysfunctional adipose tissue (AT) in obesity: unresolved inflammation, inappropriate extracellular matrix (ECM) remodeling and insufficient angiogenic potential. The interactions of these processes during AT expansion reflect both a linear...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Crewe, Clair, An, Yu Aaron, Scherer, Philipp E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199684/
https://ncbi.nlm.nih.gov/pubmed/28045400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88883
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