Substitution of leucine for isoleucine in a sequence highly conserved among retroviral envelope surface glycoproteins attenuates the lytic effect of the Friend murine leukemia virus.

Friend murine leukemia virus is a replication-competent retrovirus that contains no oncogene and that exerts lytic and leukemogenic properties. Thus, newborn mice inoculated with Friend murine leukemia virus develop severe early hemolytic anemia before appearance of erythroleukemia. To identify the...

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Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Sitbon, M, d'Auriol, L, Ellerbrok, H, André, C, Nishio, J, Perryman, S, Pozo, F, Hayes, S F, Wehrly, K, Tambourin, P
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1991
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5932
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