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Hypoxia-activated cytotoxicity of benznidazole against clonogenic tumor cells

Solid tumors contain numerous regions with insufficient oxygen concentrations, a condition termed hypoxia. Tumor hypoxia is significantly associated with metastasis, refractory to conventional cancer therapies, and poor patient survival. Therefore, eradication of hypoxic tumor cells will likely have...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Li, Quhuan, Lin, Qun, Yun, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199162/
https://ncbi.nlm.nih.gov/pubmed/27786593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1250988
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