Disruption of Desmin-Mitochondrial Architecture in Patients with Regurgitant Mitral Valves and Preserved Ventricular Function

OBJECTIVE: Recent studies have demonstrated improved outcomes in patients receiving early surgery for degenerative mitral valvular regurgitation (MR) rather than adhering to conventional guidelines for surgical intervention. However, studies providing a mechanistic basis for these findings are limit...

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Detalhes bibliográficos
Publicado no:J Thorac Cardiovasc Surg
Main Authors: Ahmed, Mustafa I, Guichard, Jason L, Soorappan, Rajasekaran Namakkal, Ahmad, Shama, Mariappan, Nithya, Litovsky, Silvio, Gupta, Himanshu, Lloyd, Steven G, Denney, Thomas S, Powell, Pamela Cox, Aban, Inmaculada, Collawn, James, Davies, James E, McGiffin, David C, Dell’Italia, Louis J
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199142/
https://ncbi.nlm.nih.gov/pubmed/27464577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2016.06.017
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