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Rofecoxib-Induced Deleterious Effects Escape Detection by Organismal Performance Assays

BACKGROUND: Organismal Performance Assays (OPAs) are a unique toxicity quantification method used to assess the safety of potentially toxic compounds, such as pharmaceuticals. OPAs utilize genetically diverse wild mice (Mus musculus) housed in semi-natural enclosures wherein exposed individuals comp...

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Detaylı Bibliyografya
Yayımlandı:J Pharm Negat Results
Asıl Yazarlar: Gaukler, Shannon M., Ruff, James S., Morrison, Linda C., Potts, Wayne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199028/
https://ncbi.nlm.nih.gov/pubmed/28042224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0976-9234.177051
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