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Rofecoxib-Induced Deleterious Effects Escape Detection by Organismal Performance Assays
BACKGROUND: Organismal Performance Assays (OPAs) are a unique toxicity quantification method used to assess the safety of potentially toxic compounds, such as pharmaceuticals. OPAs utilize genetically diverse wild mice (Mus musculus) housed in semi-natural enclosures wherein exposed individuals comp...
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| Udgivet i: | J Pharm Negat Results |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5199028/ https://ncbi.nlm.nih.gov/pubmed/28042224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0976-9234.177051 |
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