Phase I study of nintedanib in Japanese patients with advanced hepatocellular carcinoma and liver impairment

This phase I, dose‐escalation study evaluated the safety, preliminary efficacy and pharmacokinetics of nintedanib, a triple angiokinase inhibitor, in Japanese patients with advanced hepatocellular carcinoma and mild/moderate liver impairment. Thirty patients with unresectable hepatocellular carcinom...

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發表在:Cancer Sci
Main Authors: Okusaka, Takuji, Otsuka, Taiga, Ueno, Hideki, Mitsunaga, Shuichi, Sugimoto, Rie, Muro, Kei, Saito, Isao, Tadayasu, Yusuke, Inoue, Kohei, Loembé, Arsene‐Bienvenu, Ikeda, Masafumi
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198968/
https://ncbi.nlm.nih.gov/pubmed/27627050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13077
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