Safety and Pharmacokinetics of Multiple Dose myo-Inositol in Preterm Infants

BACKGROUND: Preterm infants with RDS given inositol had reduced BPD, death and severe ROP. We assessed the safety and pharmacokinetics(PK) of daily inositol to select a dose providing serum levels previously associated with benefit, and to learn if accumulation occurred when administered throughout...

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Xehetasun bibliografikoak
Argitaratua izan da:Pediatr Res
Egile Nagusiak: Phelps, Dale L., Ward, Robert M., Williams, Rick L., Nolen, Tracy L., Watterberg, Kristi L., Oh, William, Goedecke, Michael, Ehrenkranz, Richard A., Fennell, Timothy, Poindexter, Brenda B., Cotten, C. Michael, Hallman, Mikko, Frantz, Ivan D., Faix, Roger G., Zaterka-Baxter, Kristin M., Das, Abhik, Ball, M. Bethany, Lacy, Conra Backstrom, Walsh, Michele C., Carlo, Waldemar A., Sánchez, Pablo J., Bell, Edward F., Shankaran, Seetha, Carlton, David P., Chess, Patricia R., Higgins, Rosemary D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198845/
https://ncbi.nlm.nih.gov/pubmed/27074126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2016.97
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