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Gene expression alterations in the medial prefrontal cortex and blood cells in a mouse model of depression during menopause

AIMS: The prevalence of major depressive disorder (MDD) is higher in women than in men, and this may be due to the decline in estrogen levels that occurs during the menopausal transition. We studied the biological alterations in the medial prefrontal cortex (mPFC), which is a region that is highly i...

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Détails bibliographiques
Publié dans:Heliyon
Auteurs principaux: Miyata, Shigeo, Kurachi, Masashi, Sakurai, Noriko, Yanagawa, Yuchio, Ishizaki, Yasuki, Mikuni, Masahiko, Fukuda, Masato
Format: Artigo
Langue:Inglês
Publié: Elsevier 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198744/
https://ncbi.nlm.nih.gov/pubmed/28054037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2016.e00222
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