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Split spinach aptamer for highly selective recognition of DNA and RNA at ambient temperatures
Split spinach aptamer (SSA) probes for fluorescent analysis of nucleic acids were designed and tested. In SSA design, two RNA or RNA/DNA strands hybridized to a specific nucleic acid analyte and formed a binding site for DFHBI dye, which was accompanied by up to 270-fold increase in fluorescence. Th...
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| Publicado no: | Chembiochem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5198575/ https://ncbi.nlm.nih.gov/pubmed/27305425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600323 |
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