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Reverse-topology membrane scission by the ESCRT complexes

The narrow membrane necks formed during viral, exosomal, and intra-endosomal budding from membranes, cytokinesis, and related processes have interiors that are contiguous with the cytosol. The severing of these necks involves action from the opposite face of the membrane as compared to the well-char...

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Bibliographic Details
Published in:Nat Rev Mol Cell Biol
Main Authors: Schöneberg, Johannes, Lee, Il-Hyung, Iwasa, Janet H., Hurley, James H.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198518/
https://ncbi.nlm.nih.gov/pubmed/27703243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm.2016.121
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