Heterozygosity at individual amino acid sites: extremely high levels for HLA-A and -B genes.
The amino acid heterozygosities per site for HLA-A and -B loci are determined to be extremely high by combining population serotypic frequencies with amino acid sequences. For the 54 amino acid sites thought to have functional importance, the average heterozygosity per site is 0.301. Sixteen positio...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1991
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062867/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5897 |
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