Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

AKI is histologically characterized by necrotic cell death and inflammation. Diverse pathways of regulated necrosis have been reported to contribute to AKI, but the molecular regulators involved remain unclear. We explored the relative contributions of ferroptosis and necroptosis to folic acid (FA)–...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Martin-Sanchez, Diego, Ruiz-Andres, Olga, Poveda, Jonay, Carrasco, Susana, Cannata-Ortiz, Pablo, Sanchez-Niño, Maria D., Ruiz Ortega, Marta, Egido, Jesus, Linkermann, Andreas, Ortiz, Alberto, Sanz, Ana B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198282/
https://ncbi.nlm.nih.gov/pubmed/27352622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015121376
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