Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

AKI is histologically characterized by necrotic cell death and inflammation. Diverse pathways of regulated necrosis have been reported to contribute to AKI, but the molecular regulators involved remain unclear. We explored the relative contributions of ferroptosis and necroptosis to folic acid (FA)–...

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Dettagli Bibliografici
Pubblicato in:J Am Soc Nephrol
Autori principali: Martin-Sanchez, Diego, Ruiz-Andres, Olga, Poveda, Jonay, Carrasco, Susana, Cannata-Ortiz, Pablo, Sanchez-Niño, Maria D., Ruiz Ortega, Marta, Egido, Jesus, Linkermann, Andreas, Ortiz, Alberto, Sanz, Ana B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2017
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198282/
https://ncbi.nlm.nih.gov/pubmed/27352622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015121376
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